Plyglycolic Acid ( PGA) sutures are composed of glycolide/lactide copolymer which is a synthetic polyester composed of glycolide and lactide (derived from glycolic and lactic acids). PGA sutures are prepared by coating the suture with a mixture of a caprolactone/glycolide copolymer and calcium stearoyl lactylate.

PGA sutures are colored violet to increase visibility and are also available undyed.

Indicated for use in general soft tissue approximation and/or ligation, including use in ophthalmic surgery, peripheral nerve anastomosis and microsurgery for vessels less than 2mm diameter

 

PGA meets all the requirements established by the United States Pharmacopoeia (USP) and the European Pharmacopoeia (EP) for Synthetic Absorbable Surgical Sutures.

 

Features and Characteristics of  PGA Sutures:


  • Polyglycolic Acid, better know as PGA, is composed of polymers of glycolide acids.
    Absorbed by hydrolysis, absorption within 60-90 days.
  • PGA is coated to allow for easier passage through tissues with only minimal drag.
  • Coated PGA sutures facilitate:
  • Easy tissue passage
  • Precise knot placement  and  Excellent knot security
  • Smooth tie down
  • A decreased tendency to irritate tissue
  • Greater tensile strength
  • A longer absorption period
  • Soft owing to fine braid structure
  • Excellent sliding owing to a light coating (< 0.5%)
  • After 3 weeks post operation, clinical trials showed that PGA sutures maintained 51% of their tensile strength,
  • Reliable absorbability.
       1. Average 65% of the original tensile strength at 2 weeks.
       2. Average 35% of the original tensile strength at 3 weeks.
       3. Predictable absorption (loss of mass) in 60 to 90 days.

     

 

  • Clinical trials have shown that after two weeks, approximately 84% of  PGA initial strength remained. At four weeks, approximately 23%  of  PGA linear tensile strength remained.


Properties:

- Retention of 50% knot tensile strength after 18 days

Wound support - approximately 30 days

Polyglycolic Acid Suture has been found to be nonantigenic, nonpyrogenic and elicit only mild tissue reactivity during the absorption process. The absorption time for Polyglycolic Acid (PGA) is 60 to 90 days.

Post implantation Approximate % original strength remaining  

14 days
21 days
21 days
28 days

 

6-0 and larger
7-0 and smaller
6-0 and larger

85%
50%
40%
25%
 

All of the original tensile strength is lost by five weeks post implantation.

  • Absorption - Mass absorption complete between 60 and 90 days by hydrolysis
  • Synthetic - Minimal tissue reaction and predictable absorption
  • Coated - Minimal tissue drag and sawing
  • Braided - High knot security
  • Good knot snug down / adjustability
  • Colour
    Violet or undyed

Dye Used : D & C Violet (US FDA approved dye).
Coating: Calcium Stearate & Polycaprolactone.

Sterilization: Ethylene Oxide

Shelf Life : 5 years

Range:

  • U.S.P Sizes available : 8-0 to 2
  • With needle- Suture lengths from 45cms to 90cms & Needle length from 6mm to 50mm*

 

* Includes variety of Stainless Steel needles like Round Bodied cutting, reverse cutting, taper cutting, taper point, Spatula , Blunt point  etc.

  • Grade of Stainless Steel -AISI 420 and 455.

Package Info ;

Packs of 12 Pcs  & 24 Pcs

  • Dry
  • Aluminium Foil.

Maximum Suture Oversize in Diameter (mm) from U.S.P

Such variations are:

USP

EP

Diameter, Limits on average value(mm)

Knot-pull tensile
strength (kgf),
Limits on average Min

Min

Max

8-0
7-0
6-0
5-0
4-0
3-0
2-0
0
1
2
3, 4
5

0.4
0.5
0.7
1
1.5
2
0.3
3.5
4
5
6
7

0.040
0.050
0.070
0.100
0.150
0.200
0.300
0.350
0.400
0.500
0.60
0.70

0.049
0.069
0.099
0.149
0.199
0.249
0.339
0.399
0.499
0.599
0.699
0.799

0.07
0.14
0.25
0.68
0.95
1.77
2.68
3.90
5.08
6.35
-
-

 

Indication
- Gastrointestinal surgery
- Gynaecology / obstetrics
- Ophthalmic surgery
- Orthopaedics
- Urology
- Skin closure (intra, sub, skin)
- Neurosurgery
- Ligatures